Mean arterial pressure significance A mean arterial pressure in the high range could be an indication that the heart has to work much harder than it should. This is causing stress on the heart. High MAP can result in advanced heart disease, blood clots, heart attack, and stroke. When high mean arterial pressure is ongoing, heart muscles will enlarge and grow thicker, and jeopardize life expectancy. When MAP goes up quickly in a short period of time, organs can fail. A mean arterial pressure in the high range isn’t the only concern though, low is also problematic.
Low MAP can also be fatal if left untreated. Pressure readings less than 60 mm Hg must be addressed. In this case, when organs are not getting the blood they need, you can go into shock and organs can fail. Low MAP can be caused by sepsis, hemorrhaging, stroke, or some sort of trauma.
Here are some situations where perfusion of organs might come into play and impact MAP:
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