The etymology of the town's name Negotin is unclear, and there are three possibilities as to its background:
1. The Romance/Latin name origin thesis, such as the merchant place (cf. Romanian "negoț" or Spanish "negocios"), and the fact that Negotin is in a region with the presence of a significant Vlach of Serbia minority, just like its namesake Negotino in Macedonia.
2. There is also the Slavonic origin hypothesis:,, Proto-Slavonic .."něga" means "care" and the suffix "-ota//-otina" means "the action undergone or carried out", thus rendering Negotin as "a place of retreat for healing", and the city historically being located secluded amidst marshes would support the Slavonic hypothesis.
3. "Negotin" may yet have been derived from Celtic words "neges" and "tin", meaning "The fortress of war".
Negotin is first mentioned in 1530 as a settlement.
Even thought the building at the picture hosts Chinese shop with every treasure you were looking for, I tent to think the 2nd version is the most relevant to the city nowadays.