Adenoid cystic carcinoma (AdCC) is a rare form of adenocarcinoma, which is a broad term describing any cancer that begins in glandular tissues. AdCC is found mainly in the head and neck, but it can occasionally occur other locations in the body, including a woman’s uterus. AdCC most commonly occurs in the salivary glands, which consist of clusters of cells that secrete saliva scattered throughout the upper aerodigestive tract.
Regardless of where it starts, AdCC tends to spread along nerves, known as a perineural invasion, or through the bloodstream. It spreads to the lymph nodes in only about 5% to 10% of cases. The most common place of metastases, which is the spread of cancer to another part of the body, is the lung. AdCC is known for having long periods of no growth, or indolence, followed by growth spurts. However, AdCC can behave aggressively in some people, making the course of the AdCC unpredictable.
During surgery, the surgeon will remove the tumor and an area of healthy tissue surrounding it, called a margin. Surgery is considered the most successful if the margin removed during surgery is found to be “clean,” which means there is a minimum of 2 millimeters (mm) of cancer-free tissue surrounding the tumor. The extent of surgery will vary depending on the location of the tumor and the area of the body involved.
Radiation therapy is particularly effective for AdCC as an adjuvant therapy by helping to eliminate any microscopic cancer cells that may remain in the body after surgery.
Chemotherapy is generally not used for AdCC, as this type of cancer appears to be less responsive to chemotherapy than other types of cancer.
This surgery was done by my dear colleague @dr_rezamiri
سرطان غده ي بزاقي نادر آدنوسيستيكك كارسينوما
بدخيمي نادر با رشد آهسته و به اصطلاح تنبل غدد بزاقي
احتمال تهاجم به عصب و متاستاز (اغلب به ريه) وجود داره.
علايم بسته به ناحيه درگير فرق ميكنه
درمانش جراحي با مقداري از بافت سالم اطراف سپس راديو تراپي براي از بين بردن احتمالي بقاياي سلول سرطاني. شيمي درماني زياد مفيد واقع نشده در اين نوع سرطان.
اين جراحي توسط همكار عزيزم @dr_rezamiri انجام شد و من سر عمل ديگه اي بودم 😜
#ACC #Carcinoma #maxillofacialsurgeon #malignant #salivary