The show was originally called Insomnia Café ... and a bunch of other things.
In the early '90s, the creators of Friends, David Crane and Marta Kauffman, wrote a seven-page pitch for Insomnia Café. In addition to the different title, the plot itself was quite different from what we know as Friends. For example, Ross and Rachel weren't the key relationship. Instead, Joey and Monica were supposed to be love interests. After NBC bought the pilot, the title became Friends Like Us. NBC president Warren Littlefield came up with another title that was also considered, Across the Hall. By the time they shot it, the title had switched again to Six of One. When the show premiered on September 22, 1994, they had finally landed on simply Friends.