Little Apple Of Death
Hippomane Manchineel, one of the most dangerous trees in the world.
All parts of the tree contain strong toxins, some unidentified. Standing beneath the tree during rain will cause blistering of the skin from mere contact with this liquid (even a small drop of rain with the milky substance in it will cause the skin to blister). The sap has also been known to damage the paint on cars. Burning the tree may cause ocular injuries if the smoke reaches the eyes. Contact with its milky sap produces bullous dermatitis, acute keratoconjunctivitis and possibly large corneal epithelial defects.
The fruit is possibly fatal if eaten; however, "fatalities from ingestion are not reported in the modern literature" and "ingestion may produce severe gastroenteritis with bleeding, shock, bacterial superinfection, and the potential for airway compromise due to edema. Patients with a history of ingestion and either oropharyngeal burns or gastrointestinal symptoms should be evaluated for admission into hospital." /
When ingested, the fruit is reportedly "pleasantly sweet" at first, with a subsequent "strange peppery feeling ..., gradually progress[ing] to a burning, tearing sensation and tightness of the throat". Symptoms continue to worsen until the patient can "barely swallow solid food because of the excruciating pain and the feeling of a huge obstructing pharyngeal lump". - wiki